Department Web-Page

Dr. Hedi Mattoussi
Faculty

Dr. Hedi Mattoussi

Professor

PIERRE & MARIE CURIE UNIVERSITY (PARIS VI) Paris, France

  • Habilitation to Direct Research, Physical Chemistry/Nanomaterials, February 1994
  • Ph.D. Physical Chemistry, October 1987; Work done at the Collège de France, Condensed Matter Physics Laboratory.
  • M. S. Condensed Matter Physics, June 1984.
FACULTY OF SCIENCES TUNIS, Tunisia
  • B. S. Physics, June 1982; graduated with Honors.

Contact Information
Email:
mattoussi@chem.fsu.edu
Office:
4006 CSL 850.645.8615
Lab:
4702 CSL 850.645.9408
Programs of Research
 Materials
 Organic
 Physical
Research Website
Research Specialities
Chemistry of Materials, Nanoscience, Photochemistry, Spectroscopy and Dynamics, Synthesis and Catalysis
6 Graduate; 3 Postdoc; 2 Visiting

Research Interest


Hedi Mattoussi Laboratory Page



Research areas: We focus on understanding, controlling and tailoring the interfaces between inorganic nanocrystals and biological (as well as non-biological) systems.  This requires making progress on few parallel tracks, including: nanoparticle design, structural and optical characterization, ligand design and characterization, chemical interfacing of QDs, Au nanoparticles and magnetic nanocrystals with biological systems, biosensing assemblies, in vivo imaging and sensing.



Research tools: synthetic organic and inorganic chemistry; 1H NMR; X-ray and light scattering techniques; TEM and SEM; Optical spectroscopy; energy transfer (FRET); FT-IR; Cell growth; Cell imaging.



Area 1: Design, synthesis and characterization of inorganic nanocrystals


Area 2: Design, synthesis and characterization of multidentate and multifunctional ligands


Area 3: Design of nanoparticle-bioconjugates as analytical tools for sensing, imaging and diagnostics




Publications

G. Palui, F. Aldeek, W. Wang, and H. Mattoussi, “Strategies for Interfacing Inorganic Nanocrystals with Biological Systems based on Polymer-Coating,” Chem. Soc. Rev., Invited, ASAP. DOI: 10.1039/C4CS00124A
W. Wang, X. Ji, H-B. Na, M. Safi, Alexandria Smith, G. Palui, J.M. Perez, and H. Mattoussi, “A Multi-Dopamine-Modified Polymer as a Ligand Optimally Suited for Interfacing Magnetic Nanoparticles with Biological Systems,” Langmuir 30, 6197−6208 (2014). DOI: 10.1021/la500974r
F. Aldeek, M. Safi, N. Zhan G. Palui, and H. Mattoussi, “Understanding the Self-Assembly of Proteins onto Gold Nanoparticles and Quantum Dots Driven by Metal-Histidine Coordination,” ACS Nano 7, 10197–10210 (2013). DOI: 10.1021/nn404479h.
N. Zhan, G. Palui, M. Safi, and H. Mattoussi, “Multidentate Zwitterionic Ligands Provide Compact and highly biocompatible Quantum Dots,” J. Am. Chem. Soc. 135, 13786-13795 (2013). DOI: 10.1021/ja405010v