Dr. Hedi MattoussiProfessor
PIERRE & MARIE CURIE UNIVERSITY (PARIS VI) Paris, France
Research areas: We focus on understanding, controlling and tailoring the interfaces between inorganic nanocrystals and biological (as well as non-biological) systems. This requires making progress on few parallel tracks, including: nanoparticle design, structural and optical characterization, ligand design and characterization, chemical interfacing of QDs, Au nanoparticles and magnetic nanocrystals with biological systems, biosensing assemblies, in vivo imaging and sensing.
Research tools: synthetic organic and inorganic chemistry; 1H NMR; X-ray and light scattering techniques; TEM and SEM; Optical spectroscopy; energy transfer (FRET); FT-IR; Cell growth; Cell imaging.
|N. Zhan, G. Palui, and H. Mattoussi, "Multicoordinating molecular scale ligands based on the zwitterionic hydrophilic motif and lipoic acid anchors provide compact biocompatible quantum dots," Nature Protocols (2015) ASAP. P-P140409B|
|W. Wang, A. Kapur, X. Ji, M. Safi, G. Palui, V. Palomo, P.E. Dawson, and H. Mattoussi, "Photoligation of an Amphiphilic Polymer with Mixed Coordination Provides Compact and Reactive Quantum Dots," J. Am. Chem. Soc. 137, 5438?5451 (2015). DOI: 10.1021/jacs.5b00671|
|X. Ji, W. Wang and H. Mattoussi, "Effects of Separation Distance on the Charge Transfer Interactions in Quantum Dot-Dopamine Assemblies," Phys. Chem. Chem. Phys. (PCCP) 17, 10108-10117 2015. DOI: 10.1039/c5cp00462d|
|F. Aldeek, D. Hawkins, M. Safi, V. Palomo, G. Palui, P.E. Dawson, I. Alabugin, and H. Mattoussi, "UV and Sunlight Driven Photochemical Reduction of Lipoic Acid-Based Ligands to Promote Cap Exchange on Luminescent Quantum Dots," J. Am. Chem. Soc. 137, 2704-2714 (2015). DOI: 10.1021/ja512802x|