Dr. Hedi MattoussiProfessor
PIERRE & MARIE CURIE UNIVERSITY (PARIS VI) Paris, France
Research areas: We focus on understanding, controlling and tailoring the interfaces between inorganic nanocrystals and biological (as well as non-biological) systems. This requires making progress on few parallel tracks, including: nanoparticle design, structural and optical characterization, ligand design and characterization, chemical interfacing of QDs, Au nanoparticles and magnetic nanocrystals with biological systems, biosensing assemblies, in vivo imaging and sensing.
Research tools: synthetic organic and inorganic chemistry; 1H NMR; X-ray and light scattering techniques; TEM and SEM; Optical spectroscopy; energy transfer (FRET); FT-IR; Cell growth; Cell imaging.
|N. Zhan, G. Palui, J-P. Merkl and H. Mattoussi, “Bio-orthogonal Coupling as a Means of Quantifying the Ligand Density on Hydrophilic Quantum Dots,” J. Am. Chem. Soc. 2016, 138, 3190−3201. DOI: 10.1021/jacs.5b13574|
|X. Ji, W. Wang, and H. Mattoussi, “Controlling the Spectroscopic Properties of Quantum Dots via Energy Transfer and Charge Transfer Interactions: Concepts and Applications,” Nano Today 2016, 11, 98—121. DOI: 10.1016/j.nantod.2015.09.004|
|N. Zhan, G. Palui, A. Kapur, V. Palomo, P.E. Dawson, and H. Mattoussi, “Controlling the Architecture, Coordination and Reactivity of Nanoparticle Coating Utilizing an Aminoacid Central Scaffold,” J. Am. Chem. Soc., 2015, 137, 16084−16097. DOI: 10.1021/jacs.5b10359|
|F. Aldeek, D. Hawkins, M. Safi, V. Palomo, G. Palui, P.E. Dawson, I. Alabugin, and H. Mattoussi, “UV and Sunlight Driven Photochemical Reduction of Lipoic Acid-Based Ligands to Promote Cap Exchange on Luminescent Quantum Dots,” J. Am. Chem. Soc. 2015, 137, 2704−2714. DOI: 10.1021/ja512802x|