Research from the Roper group featured as HOT article in the Analyst
A recent paper by the group of Prof. Michael Roper was highlighted as a HOT article in the Analyst journal and featured on the Analyst blog and Twitter account.
Polymerase chain reaction (PCR) is a method used to amplify DNA and has enabled a revolution in numerous fields. The Roper laboratory utilizes infrared-mediated PCR in microfluidic devices to decrease the amount of time required for DNA amplification from hours to minutes. Recently, Adrian Schrell, a graduate student in the Roper lab, multiplexed the number of DNA species that could be detected by encoding the fluorescence of the signals at specific frequencies. Frequency modulation is used to encode or enhance signals in many different fields, such as NMR, MRI, and radio. By combining infrared-mediated PCR with frequency modulation detection methods, an increase in the number of DNA segments that can be screened can be realized while maintaining a simplified optical detection system. This technology should lend itself to cheaper PCR devices capable of higher throughput and reduced foot print for point of care technologies.
To learn more about the research project in the Roper laboratory, visit their website.