The Dudley and Stiegman groups continue to uncover microwave chemistry

Collaborative work from the Stiegman and Dudley labs continues to shed new light on selective heating in microwave chemistry and its potential impact on organic synthesis. Although well established in the kitchen, selective heating remains a polarizing and controversial topic in organic chemistry. The two recent papers in the Journal of Organic Chemistry (paper 1, paper 2) demonstrate beyond a reasonable doubt that selective heating of organic reaction mixtures is possible. The researchers also developed an innovative method for quantifying rate enhancements observed under microwave heating vs conventional convective heating, and new experimental protocols for maximizing the enhancement. These studies will help chemistry labs around the world make better use of their microwave reactors.

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