Anaplerotic Reactions
“Filling Up” Reactions
TCA cycle intermediates act catalytically.
Reactions to replace them when their
concentrations drop are called anaplerotic
reactions.
Four possible reactions: (Figure 20.24)
Pyruvate carboxylase
PEP carboxylase (primarily in plants)
Malic enzyme
PEP carboxykinase (Figure 20.25)