Reactions of Organometallic Compounds
(Carey, Chap. 14)

Reaction Product Notes
 
Prep. of Grignard reagent
R=any alkyl, vinyl or aryl
 
Prep. of organolithium
R=any alkyl, vinyl or aryl
Acid-base reaction
R-M very strong base
Very fast when A = O, N
   or alkyne C
 
Syn. of 1o alcohols
1-C chain extension
 
Syn. of 2o alcohols
 
Syn. of 3o alcohols
 
Syn. of 3o alcohols
2 equiv of RMgX needed
 
Syn. of carboxylic acids
 
Chap. 15 & 16

 
Prep. of organocuprate
2 equiv of R-Li needed

 
R' = alkyl, vinyl or aryl
"coupling" reaction
 
Syn. of cyclopropanes
stereospecific
organozinc intermediate
carbenoid reaction
 
Syn. of cyclopropanes
carbene intermediate

schwartz@chem.fsu.edu