John G. Dorsey

Research Group

Fundamentals of Chromatography



John G. Dorsey Bio


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Phillip B. Ogden


BS in Chemistry (2010) University of South Alabama
Office: 440 DLC
Phone: 251-709-9746

Subcritical Water Chromatography

My project involves characterizing the use of subcritical water as a mobile phase in reversed-phase liquid chromatography. The use of 100% aqueous mobile phases in lieu of traditional hydroorganic mobile phases is both less expensive and "greener". We are currently developing a relationship between SCW temperature and percent acetonitrile with regard to solvent strength of the mobile phase.  In addition, an Ethanol/Subcritical Water mobile phase will be explored as a green solution to allow for gradient elution and higher solvent strengths compared to pure SCW.