{"id":263,"date":"2026-08-24T17:07:10","date_gmt":"2026-08-24T17:07:10","guid":{"rendered":"https:\/\/www.chem.fsu.edu\/~hakansson\/?page_id=263"},"modified":"2026-09-04T16:05:53","modified_gmt":"2026-09-04T16:05:53","slug":"publications","status":"publish","type":"page","link":"https:\/\/www.chem.fsu.edu\/~hakansson\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n
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  1. Youssef, M. M.; Szot, C. W.; Ayad, M. F.; Hussein, L. A; Abdel-Ghany, M. F.; Bailey, R. C.; Mostafa, A. M.; H\u00e5kansson, K.*<\/strong> Mass Spectrometry and Enzyme Assays Refute Histone Tyrosine Sulfation. Nat. Chem Biol.<\/em> 2025<\/strong>, 21<\/em>, 1667-1670.<\/li>\n\n\n\n
  2. DeFiglia, S. A.; Lee, T.; Mikawy, N. N.; Szot, C. W.; H\u00e5kansson, K.*<\/strong> Extraction Anode Lens Effects in Gas Phase Peptide Cation-Electron Reactions. Int.<\/em> J. Mass Spectrom.<\/em> 2025<\/strong>, 509<\/em>, 117390 (invited, special issue in honor of Richard A. J. O\u2019Hair).<\/li>\n<\/ol>\n\n\n\n

        98.   Zhao, C. Y.; Borotto, N. B.; Schmidt, J.; Srivastava, K.; Lowell, A.; H\u00e5kansson, K.; Sherman, D. H.;      Ruotolo, B. T.* Gas-Phase Unfolding Reveals Stability Shifts Associated with Substrate Binding in           Modular Polyketide Synthases. J. Am. Soc. Mass Spectrom. 2025, 36, 241\u2212246.<\/p>\n\n\n\n

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    1. Mikawy, N. N.; Rojas Ramirez, C.; DeFiglia, S. A.; Szot, C. W.; Le, J.; Lantz, C.; Wei, B.; Zenaidee, M. A.; Blakney, G. T.; Nesvizhskii, A. I.; Ruotolo, B. T.; Loo, J. A.; Shabanowitz, J.; Anderson, L. C.; H\u00e5kansson, K.*<\/strong> Are Internal Fragments Observable in Electron-Based Top-Down Mass Spectrometry? Mol. Cell Proteomics<\/em> 2024<\/strong>, 23<\/em>, 100814 (invited, special issue in honor of Donald F. Hunt).<\/li>\n\n\n\n
    2. Youssef, M. M.; Szot, C. W.; Collier, L. M.; Kweon, H. K.; DeFiglia, S. A.; Ayad, M. F.; Hussein, L. A; Abdel-Ghany, M. F.; H\u00e5kansson, K.*<\/strong> Electron Capture vs. Transfer Dissociation for Site Determination of Tryptic Peptide Tyrosine Sulfation and Identification of an Unexpected Posttranslational Modification. J. Proteome Res.<\/em> 2024<\/strong>, 23<\/em>, 2386-2396.<\/li>\n\n\n\n
    3. DeFiglia, S. A.; Szot, C. W.; H\u00e5kansson, K.*<\/strong> Negative-Ion Electron Capture Dissociation of MALDI-Generated Peptide Anions. Anal. Chem<\/em>. 2024<\/strong>, 96<\/em>, 8800-8806.<\/li>\n\n\n\n
    4. Wang, N.; Dixit, S. M.; Lee, T.; DeFiglia, S. A.; Ruotolo, B. T.; H\u00e5kansson, K.*<\/strong> Salt-Bridged Peptide Anion Gaseous Structures Enable Efficient Negative Ion Electron Capture Dissociation. J. Am. Soc<\/em>. Mass Spectrom.<\/em> 2024<\/strong>, 35, 784-792 .<\/li>\n\n\n\n
    5. Kweon, H. K.; Kong, A. T.; Hersberger, K. E.; Huang, S.; Nesvizhskii, A. I.; Wang, Y.*; H\u00e5kansson, K.<\/strong>*; Andrews, P. C.* Sulfoproteomics Workflow with Precursor Ion Accurate Mass Shift Analysis Reveals Novel Tyrosine Sulfoproteins in the Golgi. J. Proteome Res<\/em>. 2024<\/strong>, 23<\/em>, 71-83.<\/li>\n\n\n\n
    6. Wang, Q; Borotto, N. B.; H\u00e5kansson, K.* Gas-Phase Hydrogen\/Deuterium Scrambling in Negative-Ion Mode Tandem Mass Spectrometry J. Am. Soc. Mass Spectrom<\/em>. 2019<\/strong>, 30<\/em>, 855-863.<\/li>\n\n\n\n
    7. Borotto, N. B.; Ileka, K. M.; Tom, C. M. B. T.; Martin, B. R.*; H\u00e5kansson, K<\/strong>.* Free Radical Initiated Peptide Sequencing for Direct Site Localization of Sulfation and Phosphorylation with Negative Ion Mode Mass Spectrometry. Anal. Chem.<\/em> 2018<\/strong>, 90<\/em>, 9682-9686.<\/li>\n\n\n\n
    8. McClory, P. J.; H\u00e5kansson, K<\/strong>.* Corona Discharge Suppression in Negative Ion Mode Nanoelectrospray Ionization via Trifluoroethanol Addition. Anal. Chem.<\/em> 2017<\/strong>, 89<\/em>, 10188-10193.<\/li>\n\n\n\n
    9. Borotto, N. B.; McClory, P. J.; Martin, B. R.*; H\u00e5kansson, K<\/strong>.* Targeted Annotation of S<\/em>-Sulfonylated Peptides by Selective Infrared Multiphoton Dissociation Mass Spectrometry. Anal. Chem<\/em>. 2017<\/strong>, 89<\/em>, 8304-8310.<\/li>\n\n\n\n
    10. Khare, D.; Hale, W. A.; Tripathi, A.; Gu, L.; Sherman, D. H.; Gerwick, W. H.; H\u00e5kansson, K.<\/strong>; Smith, J. L.* Structural Basis for Cyclopropanation by a Unique Enoyl-Acyl Carrier Protein Reductase. Structure<\/em>, 2015<\/strong>, 23<\/em>, 2213-2223.<\/li>\n\n\n\n
    11. Whicher, J. R.; Dutta, S.; Hansen, D. A.; Hale, W. A.; Chemler, J. A.; Narayan, A. R.; H\u00e5kansson, K.*<\/strong>; Sherman, D. H.*; Smith, J. L.*; Skiniotis, G.* Structural Rearrangements of a Polyketide Synthase Module during its Catalytic Cycle. Nature<\/em>, 2014<\/strong>, 510<\/em>, 560\u2013564.<\/li>\n\n\n\n
    12. Dutta, S.; Whicher, J. R.; Hansen, D. A.; Hale, W. A.; Chemler, J. A.; Narayan, A. R.; H\u00e5kansson, K.<\/strong>; Sherman, D. H.; Smith, J. L.; Skiniotis, G.* Structure of a Modular Polyketide Synthase. Nature<\/em>, 2014<\/strong>, 510<\/em>, 512\u2013517.<\/li>\n\n\n\n
    13. Zhou, W.; H\u00e5kansson, K<\/strong>.* Electron Capture Dissociation of Divalent Metal-adducted Sulfated N<\/em>-Glycans Released from Bovine Thyroid Stimulating Hormone. J. Am. Soc. Mass Spectrom<\/em>. 2013<\/strong>, 24<\/em>, 1798-1806.<\/li>\n\n\n\n
    14. Kornacki, J. R. (undergraduate author); Adamson, J. T.; H\u00e5kansson, K<\/strong>.* Electron Detachment Dissociation of Underivatized Chloride-Adducted Oligosaccharides. J. Am. Soc. Mass Spectrom<\/em>. 2012<\/strong>, 23<\/em>, 2031-2042.<\/li>\n\n\n\n
    15. Yoo, H. J.*; H\u00e5kansson, K<\/strong>. Phosphate-Containing Metabolite Enrichment with TiO2<\/sub> Micro-tips. Bull. Kor. Chem. Soc<\/em>. 2012<\/strong>, 33<\/em>, 2475-2476.<\/li>\n\n\n\n
    16. Hersberger, K. E.; H\u00e5kansson, K<\/strong>.* Characterization of O<\/em>-sulfopeptides by Negative Ion Mode Tandem Mass Spectrometry: Superior Performance of Negative-Ion Electron Capture Dissociation. Anal. Chem<\/em>. 2012<\/strong>, 84<\/em>, 6370-6377 (accelerated article)<\/strong>.<\/li>\n\n\n\n
    17. Song, H.; H\u00e5kansson, K<\/strong>.* Electron Detachment Dissociation and Negative Ion Infrared Multiphoton Dissociation of Electrosprayed Intact Proteins. Anal. Chem<\/em>. 2012<\/strong>, 84<\/em>, 871\u2013876.<\/li>\n\n\n\n
    18. Zhou, W.; H\u00e5kansson, K<\/strong>.* Electron Detachment Dissociation of Fluorescently Labeled Sialylated Oligosaccharides. Electrophoresis<\/em> 2011<\/strong>, 32<\/em>, 3526-3535 (invited, special issue on Glycomics and Glycoproteomics).<\/li>\n\n\n\n
    19. Yoo, H. J.; Wang, N.; Zhuang, S. (undergraduate author); Song, H.; H\u00e5kansson, K<\/strong>.* Negative Ion Electron Capture Dissociation: Radical-Driven Fragmentation of Charge-Increased Gaseous Peptide Anions. J. Am. Chem. Soc<\/em>. 2011<\/strong>, 133, 16790\u201316793.<\/li>\n\n\n\n
    20. Rath, C. M.; Janto, B.; Earl, J.; Ahmed, A.; Hu, F. Z.; Hiller, L.; Dahlgren, M.; Kreft, R.; Yu, F.; Wolff, J. J.; Kweon, H. K.; Christiansen, M. A.; H\u00e5kansson, K.<\/strong>; Williams, R.; Ehrlich, G.; Sherman, D. H.* Meta-omic Characterization of the Marine Invertebrate Microbial Consortium that Produces the Chemotherapeutic Natural product ET-743. ACS Chem. Biol<\/em>. 2011<\/strong>, 6, 1244-1256.<\/li>\n\n\n\n
    21. Zhou, W.; H\u00e5kansson, K.*<\/strong> Structural Determination of Carbohydrates by Fourier Transform Tandem Mass Spectrometry. Curr. Proteomics<\/em> 2011<\/strong>, 8<\/em>, 297-308.<\/li>\n\n\n\n
    22. Kalli, A.; Grigorean, G.; H\u00e5kansson, K<\/strong>.* Electron Induced Dissociation of Singly Deprotonated Peptides. J. Am. Soc. Mass Spectrom<\/em>. 2011<\/strong>, 22<\/em>, 2209-2221.<\/li>\n\n\n\n
    23. Ding, Y.; Rath, C. M.; Bolduc, K. L.; H\u00e5kansson, K<\/strong>.; Sherman, D. H.* Chemoenzymatic Synthesis of Cryptophycin Anticancer Agents by an Ester Bond Forming Nonribosomal Peptide Synthetase Module. J. Am. Chem. Soc<\/em>. 2011<\/strong>, 133<\/em>, 14492\u201314495.<\/li>\n\n\n\n
    24. Bonnett, S. A.; Rath, C. M.; Shareef, R.; Joels, J. R.; Chemler, J.; H\u00e5kansson, K<\/strong>; Reynolds, K.; Sherman, D. H.* Acyl-CoA Subunit Selectivity in the Terminal Pikromycin Polyketide Synthase Module: Steady-State Kinetics and Active-Site Occupancy Analysis by FTICR-MS. Chem. Biol.<\/em> 2011<\/strong>, 18<\/em>, 1075-1081.<\/li>\n\n\n\n
    25. Liu H. C.; H\u00e5kansson, K<\/strong>.* Electron Capture Dissociation of Divalent Metal-Adducted Sulfated Oligosaccharides. Int. J. Mass Spectrom<\/em>. 2011<\/strong>, 305<\/em>, 170\u2013177 (invited, special issue honoring Catherine E. Costello).<\/li>\n\n\n\n
    26. 72. Yoo, J.; H\u00e5kansson, K.*<\/strong> Determination of Phospholipid Regiochemistry by Ag(I) Adduction and Tandem Mass Spectrometry. Anal. Chem.<\/em> 2011<\/strong>, 83<\/em>, 1275-1283.<\/li>\n\n\n\n
    27. H\u00e5kansson, K<\/strong>.*; Klassen, J. S.* Ion Activation Methods for Tandem Mass Spectrometry. In Electrospray and MALDI Mass Spectrometry: Fundamentals, Instrumentation, Practicalities, and Biological Applications<\/em>; Cole, R. B. Ed.; John Wiley & Sons: New York, 2010<\/strong>; pp 571-630.<\/li>\n\n\n\n
    28. Buchholz, T. J.; Rath, C. M.; Lopanik, N. B.; Gardner, N. P.; H\u00e5kansson, K.<\/strong>; Sherman, D. H.* Polyketide \uf062-Branching in Bryostatin Biosynthesis: Identification of Surrogate Acetyl-ACP Donors for BryR, an HMG-ACP Synthase. Chem. Biol<\/em>. 2010<\/strong>, 17<\/em>, 1092-1100.<\/li>\n\n\n\n
    29. Khare, D.; Wang, B.; Gu, L.; Razelun, J.; Sherman, D. H.; Gerwick, W. H.; H<\/strong>\u00e5<\/strong>kansson K.<\/strong>; Smith, J. L.* Crystal Structure of the Halogenase Domain in Curacin A Biosynthesis: Conformational Switch Triggered by \u03b1-Ketoglutarate. Proc. Natl. Acad. Sci. U.S.A<\/em>. 2010<\/strong>, 107<\/em>, 14099-14104.<\/li>\n\n\n\n
    30. Yoo, H. J.; H\u00e5kansson, K<\/strong>.* Determination of Double Bond Location in Fatty Acids by Manganese Adduction and Electron Induced Dissociation. Anal. Chem<\/em>. 2010<\/strong>, 82,<\/em> 6940\u20136946.<\/li>\n\n\n\n
    31. Kalli, A.; H\u00e5kansson, K<\/strong>.* Electron Capture Dissociation of Highly Charged Proteolytic Peptides from Lys N, Lys C and Glu C Digestion. Mol. Biosyst<\/em>. 2010<\/strong>, 6<\/em>, 1668-1681 (invited, special issue on Emerging Investigators).<\/li>\n\n\n\n
    32. Yoon, M.; Song, H.; H\u00e5kansson, K<\/strong>.; Marsh, E. N. G.* Hydrogen Tunneling in Adenosylcobalamin-Dependent Glutamate Mutase: Evidence from Intrinsic Kinetic Isotope Effects Measured by Intra<\/em>-molecular Competition. Biochemistry<\/em>, 2010<\/strong>, 49<\/em>, 3168-3173.<\/li>\n\n\n\n
    33. Matson, J. S.; Yoo, H. J.; H\u00e5kansson, K.; DiRita, V. J.* Polymyxin B Resistance in El Tor Vibrio cholerae<\/em> Requires Lipid Acylation Catalyzed by MsbB. J. Bacteriol<\/em>. 2010, 192, 2044-2052.<\/li>\n\n\n\n
    34. Yang, J.; H\u00e5kansson, K<\/strong>.* Tandem Mass Spectrometry of Nucleic Acids. In Mass Spectrometry of Nucleosides and Nucleic Acids<\/em>; Banoub, J. H.; Limbach, P. A. Eds.; CRC Press: Boca Raton, 2009<\/strong>; pp 95-116.<\/li>\n\n\n\n
    35. Gu, L.; Wang, B.; Kulkarni, A.; Gehret, J. J.; Lloyd, K.; Gerwick, L.; Gerwick, W. H.; Wipf, P.; H\u00e5kansson, K.<\/strong>; Smith, J. L.; Sherman, D. H.* Polyketide Decarboxylative Chain Termination Preceded by O<\/em>-Sulfonation in Curacin A Biosynthesis. J. Am. Chem. Soc.<\/em> 2009<\/strong>, 131<\/em>, 16033-16035.<\/li>\n\n\n\n
    36. Majmudar, C. Y.; Wang, B.; Lum, J. K.; H\u00e5kansson, K.*; Mapp, A. K.* A High Resolution Interaction Map of Three Transcriptional Activation Domains with an Essential Co-activator from Photo Cross-Linking and Multiplexed Mass Spectrometry. Angew. Chem. Int. Ed<\/em>. 2009, 48<\/em>, 7021-7024 (selected as VIP).<\/li>\n\n\n\n
    37. Gu, L.; Wang, B.; Kulkarni, A.; Geders, T. W.; Grindberg, R. V.; Gerwick, L. G.; H\u00e5kansson, K.<\/strong>; Wipf, P.; Smith, J. L.; Gerwick, W. H.; Sherman, D. H.* Metamorphic Enzyme Assembly in Polyketide Diversification. Nature<\/em> 2009<\/strong>, 459<\/em>, 731-735.<\/li>\n\n\n\n
    38. Yang, J.; H\u00e5kansson, K.*<\/strong> Characterization of Oligodeoxynucleotide Fragmentation Pathways in Infrared Multiphoton Dissociation and Electron Detachment Dissociation by Fourier Transform Ion Cyclotron Double Resonance. Eur. J. Mass Spectrom.<\/em> 2009<\/strong>, 15<\/em>, 293-304 (invited, special issue honoring Peter J. Derrick).<\/li>\n\n\n\n
    39. Mo, J. J.; Todd, G. C.; H\u00e5kansson, K<\/strong>.* Characterization of Nucleic Acid Higher Order Structure by Gas-Phase H\/D Exchange in a Quadrupole-FT-ICR Mass Spectrometer. Biopolymers<\/em> 2009<\/strong>, 91<\/em>, 256-264 (invited, special issue dedicated to advances in the investigation of nucleic acids and nucleic acid assemblies).<\/li>\n\n\n\n
    40. Wilson-Stanford, S.; Kalli, A.; H\u00e5kansson, K.<\/strong>; Kastrantas, J.;.Orugunty, R. S.; Breukink, E.; Smith, L.* Oxidation of Lanthionines Renders the Lantibiotic Nisin Inactive. Appl. Environ. Microbiol<\/em>. 2009<\/strong>, 75<\/em>, 1381-1387.<\/li>\n\n\n\n
    41. Ditzler, M. A.; Rueda, D.; Mo, J. J.; H\u00e5kansson, K<\/strong>.; Walter, N. G.* A Rugged Free Energy Landscape Separates Multiple Functional RNA Folds Throughout Denaturation. Nucleic Acids Res.<\/em> 2008<\/strong>, 36<\/em>, 7088-7099.<\/li>\n\n\n\n
    42. Lopanik, N. B.; Shields, J. A.; Buchholz, T. J.; Rath, C. M.; Hothersall, J.; Haygood, M. G.; H\u00e5kansson, K.<\/strong>; Thomas, C. M.; Sherman, D. H.* In vivo<\/em> and in vitro Trans<\/em>-Acylation by BryP, the Putative Bryostatin Pathway Acyltransferase Derived from an Uncultured Marine Symbiont. Chem. Biol<\/em>. 2008<\/strong>, 15<\/em>, 1175-1186.<\/li>\n\n\n\n
    43. Yang, J.; H\u00e5kansson, K.*<\/strong> Characterization and Optimization of Electron Detachment Dissociation Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. Int. J. Mass Spectrom<\/em>. 2008<\/strong>, 276<\/em>, 144-148 (invited, special issue on ion-electron and ion-ion interactions).<\/li>\n\n\n\n
    44. Kalli, A.; H\u00e5kansson, K<\/strong>.* Comparison of the Electron Capture Dissociation Fragmentation Behavior of Doubly- and Triply-protonated Peptides from Trypsin, Glu-C and Chymotrypsin Digestion. J. Proteome Res<\/em>. 2008<\/strong>, 7<\/em>, 2834-2844.<\/li>\n\n\n\n
    45. Liu, H. C.; Yoo, H. J.; H\u00e5kansson, K<\/strong>.* Characterization of Phosphate-Containing Metabolites by Calcium Adduction and Electron Capture Dissociation. J. Am. Soc. Mass Spectrom.<\/em> 2008<\/strong>, 19<\/em>, 799-808 (invited, special issue honoring Roman A. Zubarev).<\/li>\n\n\n\n
    46. Kweon H. K.; H\u00e5kansson, K<\/strong>.* Metal Oxide-Based Enrichment Combined with Gas-Phase Ion-Electron Reactions for Improved Mass Spectrometric Characterization of Protein Phosphorylation. J. Proteome Res.<\/em> 2008<\/strong>, 7<\/em>, 749-755.<\/li>\n\n\n\n
    47. Adamson, J. T.; H\u00e5kansson, K<\/strong>.* Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for Lectin Analysis. In Lectins: Analytical Technologies<\/em>; Nilsson, C. L. Ed.; Elsevier: Amsterdam, 2007<\/strong>; pp 343-371.<\/li>\n\n\n\n
    48. Geders, T. W.; Gu, L.; Mowers, J. C.; Liu, H. C.; Gerwick, W. H.; H\u00e5kansson, K.<\/strong>; Sherman, D. H.*; Smith, J. L.* Crystal Structure of the ECH2<\/sub> Catalytic Domain of CurF from Lyngbya majuscula<\/em>: Insights into a Decarboxylase Involved in Polyketide Chain b-branching. J. Biol. Chem.<\/em> 2007<\/strong>, 282<\/em>, 35954\u201335963.<\/li>\n\n\n\n
    49. Adamson, J. T.; H\u00e5kansson, K.* Electron Detachment Dissociation of Neutral and Sialylated Oligosaccharides. J. Am. Soc. Mass Spectrom<\/em>. 2007, 18<\/em>, 2162-2172.<\/li>\n\n\n\n
    50. Goldstein, I. J.*; Winter, H. C.; Aurandt, J.; Confer, L.; Adamson, J. T.; H\u00e5kansson, K.<\/strong>; Remmer, H. A New a-Galactosyl-Binding Protein from the Mushroom Lyophyllum<\/em> decastes<\/em>. Arch. Biochem. Biophys.<\/em> 2007<\/strong>, 467<\/em>, 268\u2013274.<\/li>\n\n\n\n
    51. Gu, L.; Geders, T. W.; Wang, B.; Gerwick, W. H.; H\u00e5kansson, K.; Smith, J. L.; Sherman, D. H.* GNAT-Like Strategy for Polyketide Chain Initiation. Science<\/em> 2007, 318<\/em>, 970-974.<\/li>\n\n\n\n
    52. Yoon, M.; Kalli, A.; Lee, H. Y.; H\u00e5kansson, K<\/strong>.; Marsh, E. N. G.* Intrinsic Deuterium Kinetic Isotope Effects in Glutamate Mutase Measured by an Intramolecular Competition Experiment. Angew. Chem<\/em>. Int. Ed<\/em>. 2007<\/strong>, 46<\/em>, 8455-8459.<\/li>\n\n\n\n
    53. Liu, H. C.; H\u00e5kansson, K<\/strong>.* Abundant b<\/em>-Type Ions Produced in Electron Capture Dissociation of Peptides without Basic Amino Acid Residues. J. Am. Soc. Mass Spectrom<\/em>. 2007<\/strong>, 18<\/em>, 2007-2013.<\/li>\n\n\n\n
    54. Mo, J. J.; H\u00e5kansson, K<\/strong>.* Oligonucleotide Gas-Phase Hydrogen\/Deuterium Exchange with D2<\/sub>S in the Collision Cell of a Quadrupole-Fourier Transform Ion Cyclotron Resonance Mass Spectrometer. Anal. Chem<\/em>. 2007<\/strong>, 79<\/em>, 7893-7898.<\/li>\n\n\n\n
    55. Yoo, H. J.; Liu, H. C.; H\u00e5kansson, K<\/strong>.* Infrared Multiphoton Dissociation and Electron-Induced Dissociation as Alternative MS\/MS Strategies for Metabolite Identification. Anal. Chem<\/em>. 2007<\/strong>, 79<\/em>, 7858-7866.<\/li>\n\n\n\n
    56. Liu, H. C.; Lee, J. Y; Sherman, D. H.; H\u00e5kansson, K.* Collision Activated Dissociation, Infrared Multiphoton Dissociation, and Electron Capture Dissociation of the Bacillus anthracis<\/em> Siderophore Petrobactin and its Metal Ion Complexes. J. Am. Soc. Mass Spectrom<\/em>. 2007, 18<\/em>, 842-849.<\/li>\n\n\n\n
    57. Kalli, A.; H\u00e5kansson, K<\/strong>.* Preferential Cleavage of S-S and C-S Bonds in Electron Detachment Dissociation and Infrared Multiphoton Dissociation of Disulfide-Linked Peptide Anions. Int. J. Mass Spectrom<\/em>. 2007<\/strong>, 263<\/em>, 71-81.<\/li>\n\n\n\n
    58. Adamson, J. T.; H\u00e5kansson, K<\/strong>.* Electron Capture Dissociation of Oligosaccharides Ionized with Alkali, Alkaline Earth, and Transition Metals. Anal. Chem<\/em>. 2007<\/strong>, 79<\/em>, 2901-2910.<\/li>\n\n\n\n
    59. Lee, J. Y.; Janes, B. K.; Passalacqua, K. D.; Pfleger, B.; Bergman, N. H.; Liu, H. C.; H\u00e5kansson, K.; Somu, R. V.; Aldrich, C. C.; Cendrowski, S.; Hanna, P.; Sherman, D. H.* Biosynthetic Analysis of the Petrobactin Siderophore Pathway from Bacillus anthracis<\/em>. J. Bacteriol<\/em>. 2007, 189<\/em>, 1698-1710.<\/li>\n\n\n\n
    60. Liu, H. C.; H\u00e5kansson, K.*<\/strong> Divalent Metal Ion-Peptide Interactions Probed by Electron Capture Dissociation of Trications. J. Am. Soc. Mass Spectrom.<\/em> 2006<\/strong>, 17<\/em>, 1731-1741.<\/li>\n\n\n\n
    61. Liu, H. C.; H\u00e5kansson, K<\/strong>.* Electron Capture Dissociation of Tyrosine O-Sulfated Peptides Complexed with Divalent Metal Cations. Anal. Chem.<\/em> 2006<\/strong>, 78<\/em>, 7570-7576.<\/li>\n\n\n\n
    62. Yang, J.; H\u00e5kansson, K.*<\/strong> Fragmentation of Oligoribonucleotides from Gas-Phase Ion-Electron Reactions. J. Am. Soc. Mass Spectrom<\/em>. 2006<\/strong>, 17<\/em>, 1369-1375 (invited, special issue honoring James A. McCloskey).<\/li>\n\n\n\n
    63. Mo, J. J.; H\u00e5kansson, K.*<\/strong> Characterization of Nucleic Acid Higher Order Structure by Tandem High Resolution Mass Spectrometry. Anal. Bioanal. Chem.<\/em> 2006<\/strong>, 386<\/em>, 675-681 (invited, Young Investigators issue).<\/li>\n\n\n\n
    64. Gu, L.; Jia, J.; Liu, H. C.; H\u00e5kansson, K.<\/strong>; Gerwick, W. H.; Sherman, D. H.* Metabolic Coupling of Dehydration in the Curacin A Pathway: Functional Identification of a Mechanistically Diverse Enzyme Pair. J. Am. Chem. Soc<\/em>. 2006<\/strong>, 128<\/em>, 9014-9015.<\/li>\n\n\n\n
    65. Kweon, H. K.; H\u00e5kansson, K.*<\/strong> Selective Zirconium Dioxide-Based Enrichment of Phosphorylated Peptides for Mass Spectrometric Analysis. Anal. Chem.<\/em> 2006<\/strong>, 78<\/em>, 1743-1749 (accelerated article, featured as a 2006 Most-Cited Article for that journal, and as an ACS \u201chot paper\u201d in January 2008)<\/strong>.<\/li>\n\n\n\n
    66. Adamson, J. T.; H\u00e5kansson, K.*<\/strong> Infrared Multiphoton Dissociation and Electron Capture Dissociation of High Mannose-Type Glycopeptides. J. Proteome Res.<\/em> 2006<\/strong>, 5<\/em>, 493-501.<\/li>\n\n\n\n
    67. Kweon, H. K.; H\u00e5kansson, K.*<\/strong> Site-Specific Amide Hydrogen Exchange in Melittin Probed by Electron Capture Dissociation Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. Analyst<\/em> 2006<\/strong>, 131<\/em>, 275-280 (invited, special issue on Emerging Investigators).<\/li>\n\n\n\n
    68. Yang, J.; Mo, J. J.; Adamson, J. T.; H\u00e5kansson, K.*<\/strong> Characterization of Oligodeoxynucleotides by Electron Detachment Dissociation Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. Anal. Chem<\/em>. 2005<\/strong>, 77<\/em>, 1876-1882.<\/li>\n\n\n\n
    69. Cooper, H. J.; H\u00e5kansson, K.<\/strong>; Marshall, A. G.* The Role of Electron Capture Dissociation in Biomolecular Analysis. Mass Spectrom. Rev.<\/em> 2005,<\/strong> 24<\/em>, 201-222 (2005-2006 second most cited article for that journal)<\/strong>.<\/li>\n\n\n\n
    70. Schultz, K. N.; H\u00e5kansson, K.*<\/strong> Rapid Electron Capture Dissociation of Mass-Selectively Accumulated Oligonucleotide Dications. Int. J. Mass Spectrom.<\/em> 2004<\/strong>, 234<\/em>, 123-130.<\/li>\n\n\n\n
    71. Hurd, T. W.; Fan, S.; Liu, A.; Kweon, H. K.; H\u00e5kansson, K.<\/strong>; Margolis, B.* Phosphorylation-dependent Binding of 14-3-3 to the Polarity Protein Par3 Regulates Cell Polarity in Mammalian Epithelia. Curr. Biol<\/em>. 2003,<\/strong> 13<\/em>, 2082-2090.<\/li>\n<\/ol>\n\n\n\n

      POSTDOCTORAL PUBLICATIONS<\/strong><\/p>\n\n\n\n

        \n
      1. Chalmers, M. J.; H\u00e5kansson, K.<\/strong>; Johnson, R.; Smith, R.; Shen, J.; Emmett, M. R.; Marshall, A. G. Characterization of Protein Kinase A Phosphorylation with Tandem Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. Proteomics<\/em> 2004,<\/strong> 4<\/em>, 970-981.<\/li>\n\n\n\n
      2. He, F.; Emmett, M. R.; H\u00e5kansson, K.<\/strong>; Hendrickson, C. L.; Marshall, A. G. Theoretical and Experimental Prospects for Protein Identification Based Solely on Accurate Mass Measurement. J. Proteome Res<\/em>. 2004<\/strong>, 3<\/em>, 61-67.<\/li>\n\n\n\n
      3. H\u00e5kansson, K.<\/strong>; Emmett, M. R.; Marshall, A. G.; Davidsson, P.; Nilsson, C. L. Structural Analysis of Gel-Separated Glycoproteins from Human Cerebrospinal Fluid by Tandem High Resolution Mass Spectrometry. J. Proteome Res<\/em>. 2003,<\/strong> 2<\/em>, 581-588.<\/li>\n\n\n\n
      4. H\u00e5kansson, K.<\/strong>; Cooper, H. J.; Hudgins, R. R.; Nilsson, C. L. High Resolution Tandem Mass Spectrometry for Structural Biochemistry. Curr. Org. Chem.<\/em> 2003,<\/strong> 7,<\/em> 1503-1525.<\/li>\n\n\n\n
      5. Cooper, H. J.; H\u00e5kansson, K.<\/strong>; Marshall, A. G.; Hudgins, R. R.; Haselmann, K. F.; Kjeldsen, F.; Budnik, B. A.; Polfer, N. C.; Zubarev, R. A. The Diagnostic Value of Amino Acid Side-chain Losses in Electron Capture Dissociation of Polypeptides. Eur. J. Mass Spectrom<\/em>. 2003,<\/strong> 9,<\/em> 221-222.<\/li>\n\n\n\n
      6. Cooper, H. J.; Hudgins, R. R.; H\u00e5kansson, K.<\/strong>; Marshall, A. G. Secondary Fragmentation of Linear Peptides in Electron Capture Dissociation. Int. J. Mass Spectrom.<\/em> 2003,<\/strong> 228,<\/em> 723-728.<\/li>\n\n\n\n
      7. H\u00e5kansson, K.<\/strong>; Chalmers, M. J.; Quinn, J. P.; McFarland, M. A.; Hendrickson, C. L.; Marshall, A. G. Combined Electron Capture and Infrared Multiphoton Dissociation for Multistage MS\/MS in an FT-ICR Mass Spectrometer. Anal. Chem<\/em>. 2003,<\/strong> 75,<\/em> 3256-3262.<\/li>\n\n\n\n
      8. Fagerquist, C. K.; Hudgins, R. R.; Emmett, M. R.; H\u00e5kansson, K.<\/strong>; Marshall, A. G. An Antibiotic Linked to Peptides and Proteins is Released by Electron Capture Dissociation Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. J. Am. Soc. Mass Spectrom.<\/em> 2003,<\/em><\/strong> 14,<\/em> 302-310.<\/li>\n\n\n\n
      9. H\u00e5kansson, K.<\/strong>; Hudgins, R. R.; Marshall, A. G.; O\u2019Hair, R. A. J. Electron Capture Dissociation and Infrared Multiphoton Dissociation of Oligodeoxynucleotide Dications. J. Am. Soc. Mass Spectrom.<\/em> 2003,<\/strong> 14,<\/em> 23-41.<\/li>\n\n\n\n
      10. H\u00e5kansson, K.<\/strong>; Quenzer, T. L.; Marshall, A. G.; Emmett, M. R. Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for Peptide Analysis. In Mass Spectrometry and Hyphenated Techniques in Neuropeptide Research<\/em>; Ekman, R.; Silberring, J., Eds.; Wiley: New York, 2002<\/strong>; pp 323-343.<\/li>\n\n\n\n
      11. Nilsson, C. L.; Cooper, H. J.; H\u00e5kansson, K.<\/strong>; Marshall, A. G.; \u00d6stberg, Y.; Lavrinovicha, M.; Bergstr\u00f6m, S. Characterization of the P13 Membrane Protein of Borrelia burgdorferi<\/em> by Mass Spectrometry. J. Am. Soc. Mass Spectrom.<\/em> 2002,<\/strong> 13,<\/em> 295-299.<\/li>\n\n\n\n
      12. Cooper, H. J.; Hudgins, R. R.; H\u00e5kansson, K.<\/strong>; Marshall, A. G. Characterization of Amino Acid Side Chain Losses in Electron Capture Dissociation. J. Am. Soc. Mass Spectrom.<\/em> 2002,<\/strong> 13<\/em>, 241-249.<\/li>\n\n\n\n
      13. H\u00e5kansson, K.<\/strong>; Cooper, H. J.; Emmett, M. R.; Costello, C. E.; Marshall, A. G.; Nilsson, C. L. Electron Capture Dissociation and Infrared Multiphoton Dissociation MS\/MS of an N-Glycosylated Tryptic Peptide To Yield Complementary Sequence Information. Anal. Chem.<\/em> 2001,<\/strong> 73,<\/em> 4530-4536.<\/li>\n\n\n\n
      14. H\u00e5kansson, K.<\/strong>; Emmett, M. R.; Hendrickson, C. L.; Marshall, A. G. High Sensitivity Tandem Electron Capture Dissociation FTICR Mass Spectrometry of Microelectrosprayed Peptides. Anal. Chem.<\/em> 2001,<\/strong> 73,<\/em> 3605-3610.<\/li>\n<\/ol>\n\n\n\n

        GRADUATE STUDENT PUBLICATIONS<\/strong><\/p>\n\n\n\n

          \n
        1. Hagman, C.; H\u00e5kansson, P.; Buijs, J.; H\u00e5kansson, K<\/strong>. Inter-Molecular Migration During Collisional Activation Monitored by Hydrogen\/Deuterium Exchange FT-ICR Tandem Mass Spectrometry. J. Am. Soc. Mass Spectrom<\/em>. 2004,<\/strong> 15<\/em>, 639-646.<\/li>\n\n\n\n
        2. Buijs, J.; Hagman, C.; H\u00e5kansson, K.<\/strong>; Richter, J. H.; H\u00e5kansson, P.; Oscarsson, S. Inter- and Intra-molecular Migration of Peptide Amide Hydrogens during Electrospray Ionization. J. Am. Soc. Mass Spectrom<\/em>. 2001,<\/strong> 12,<\/em> 410-419.<\/li>\n\n\n\n
        3. Palmblad, M.; H\u00e5kansson, K.<\/strong>; H\u00e5kansson, P.; Feng, X. D.; Cooper, H. J.; Giannakopulos, A. E.; Green, P. S.; Derrick, P. J. A 9.4 T Fourier Transform Ion Cyclotron Resonance Mass Spectrometer: Description and Performance. Eur. J. Mass Spectrom.<\/em> 2000,<\/strong> 6,<\/em> 267-275.<\/li>\n\n\n\n
        4. Buijs, J.; H\u00e5kansson, K.<\/strong>; Hagman, C.; H\u00e5kansson, P.; Oscarsson, S. A New Method for the Accurate Determination of the Isotopic State of Single Amide Hydrogens within Peptides using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. Rapid Commun. Mass Spectrom.<\/em> 2000,<\/strong> 14,<\/em> 1751-1756.<\/li>\n\n\n\n
        5. H\u00e5kansson, K.<\/strong>; Coorey, R. V.; Zubarev, R. A.; Talrose, V. L.; H\u00e5kansson, P. Low Mass Ions Observed in Plasma Desorption Mass Spectrometry of High Explosives. J. Mass Spectrom.<\/em> 2000,<\/strong> 35,<\/em> 337-346.<\/li>\n\n\n\n
        6. H\u00e5kansson, K.<\/strong>; Axelsson, J.; Palmblad, M.; H\u00e5kansson, P. Mechanistic Studies of Multipole Storage Assisted Dissociation. J. Am. Soc. Mass Spectrom.<\/em> 2000,<\/strong> 11,<\/em> 210-217.<\/li>\n\n\n\n
        7. H\u00e5kansson, K.<\/strong>; Zubarev, R. A.; H\u00e5kansson, P.; Laiko, V.; Dodonov, A. F. Design and Performance of an Electrospray Ionization Time-of-flight Mass Spectrometer. Rev. Sci. Instrum<\/em>. 2000,<\/strong> 71,<\/em> 36-41.<\/li>\n\n\n\n
        8. Blomqvist, M.; Bergquist, J.; Westman, A.; H\u00e5kansson, K.<\/strong>; H\u00e5kansson, P.; Fredman, P.; Ekman, R. Identification of Defensins in Human Lymphocyte Nuclei. Eur. J. Biochem.<\/em> 1999,<\/strong> 263,<\/em> 312-318.<\/li>\n\n\n\n
        9. Axelsson, J.; H\u00e5kansson, K.<\/strong>; Palmblad, M.; H\u00e5kansson, P. A Method to Significantly Lessen the Sample Contamination of the Vacuum Interface of an On-axis Electrospray Ion Source by Adding a Mechanical Shutter. Rapid Commun. Mass Spectrom.<\/em> 1999,<\/strong> 13,<\/em> 1550-1550.<\/li>\n\n\n\n
        10. H\u00e5kansson, K.<\/strong>; Zubarev, R. A.; Coorey, R. V.; Talrose, V. L.; H\u00e5kansson, P. Interaction between Explosive- and Analyte Layers in Explosive-Matrix Assisted Plasma Desorption Mass Spectrometry. Rapid Commun. Mass Spectrom.<\/em> 1999,<\/strong> 13,<\/em> 1169-1174.<\/li>\n\n\n\n
        11. Axelsson, J.; Palmblad, M.; H\u00e5kansson, K.<\/strong>; H\u00e5kansson, P. Electron Capture Dissociation of Substance-P using a Commercially Available FT-ICR Mass Spectrometer. Rapid Commun. Mass Spectrom.<\/em> 1999,<\/strong> 13<\/em>, 474-477.<\/li>\n\n\n\n
        12. H\u00e5kansson, K.<\/strong>; Zubarev, R.; H\u00e5kansson, P. Combination of Nozzle-skimmer Fragmentation and Partial Acid Hydrolysis in Electrospray Ionization Time-of-flight Mass Spectrometry of Synthetic Peptides. Rapid Commun. Mass Spectrom<\/em>. 1998,<\/strong> 12,<\/em> 705-711.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

              98.   Zhao, C. Y.; Borotto, N. B.; Schmidt, J.; Srivastava, K.; Lowell, A.; H\u00e5kansson, K.; Sherman, D. H.;      Ruotolo, B. T.* Gas-Phase Unfolding Reveals Stability Shifts Associated with Substrate Binding in           Modular Polyketide Synthases. J. Am. Soc. Mass Spectrom. 2025, 36, 241\u2212246. POSTDOCTORAL PUBLICATIONS GRADUATE STUDENT […]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-263","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.chem.fsu.edu\/~hakansson\/wp-json\/wp\/v2\/pages\/263","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.chem.fsu.edu\/~hakansson\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.chem.fsu.edu\/~hakansson\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.chem.fsu.edu\/~hakansson\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.chem.fsu.edu\/~hakansson\/wp-json\/wp\/v2\/comments?post=263"}],"version-history":[{"count":4,"href":"https:\/\/www.chem.fsu.edu\/~hakansson\/wp-json\/wp\/v2\/pages\/263\/revisions"}],"predecessor-version":[{"id":381,"href":"https:\/\/www.chem.fsu.edu\/~hakansson\/wp-json\/wp\/v2\/pages\/263\/revisions\/381"}],"wp:attachment":[{"href":"https:\/\/www.chem.fsu.edu\/~hakansson\/wp-json\/wp\/v2\/media?parent=263"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}