{"id":100,"date":"2024-01-22T22:34:04","date_gmt":"2024-01-22T22:34:04","guid":{"rendered":"https:\/\/www.chem.fsu.edu\/~lzhu\/?page_id=100"},"modified":"2026-01-30T02:52:02","modified_gmt":"2026-01-30T02:52:02","slug":"publications","status":"publish","type":"page","link":"https:\/\/www.chem.fsu.edu\/~lzhu\/publications\/","title":{"rendered":"Publications 2021-Present"},"content":{"rendered":"<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.joc.5c00857\"><img loading=\"lazy\" decoding=\"async\" width=\"996\" height=\"467\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2025KNW.jpeg\" alt=\"\" class=\"wp-image-441\" style=\"aspect-ratio:2.132825517733873;width:488px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2025KNW.jpeg 996w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2025KNW-300x141.jpeg 300w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2025KNW-768x360.jpeg 768w\" sizes=\"auto, (max-width: 996px) 100vw, 996px\" \/><\/a><\/figure>\n<\/div>\n\n\n<p>&#8220;<strong>Copper-Catalyzed Conjugation between Nitrile Imines and Terminal Alkynes<\/strong>&#8221; Weeks, K. N.; Zhu, L. <em>J. Org. Chem<\/em>. <strong>2025<\/strong>, <em>90<\/em>, 8329-8339.<\/p>\n\n\n\n<p class=\"has-text-align-center\">############################################################################<br><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.joc.4c02920\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"253\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2025KNL-1024x253.jpeg\" alt=\"\" class=\"wp-image-431\" style=\"aspect-ratio:4.047583195301913;width:478px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2025KNL-1024x253.jpeg 1024w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2025KNL-300x74.jpeg 300w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2025KNL-768x190.jpeg 768w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2025KNL.jpeg 1283w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n<\/div>\n\n\n<p>&#8220;<strong>DABCO-Catalyzed Nucleophilic Aromatic Substitution and Its Use in Improving the Synthesis of O<sup>2<\/sup>-Benzylcytosines as Substrates of CLIP-tag<\/strong>&#8221; Little, K. N.; Ofosu Addai, G.; Stanwood, C. C.; Bucag, C. F. T.; Lin, X.; Chen, B.; Whittington, A. C.; Zhu, L.  <em>J. Org. Chem<\/em>. <strong>2025<\/strong>, <em>90<\/em>, 8001-8012.<\/p>\n\n\n\n<p class=\"has-text-align-center\">############################################################################<\/p>\n\n\n\n<p>&#8220;<strong><a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0304736#\">Scalable lipid droplet microarray fabrication, validation, and screening<\/a><\/strong>&#8221; Bell, T. N., Kusi-Appiah, A. E., Tocci, V., Lyu, P., Zhu, L., Zhu, F., Winkle, D. V., Cao, H., Singh, M. S., Lenhert, S. <em>PLoS ONE<\/em> <strong>2024<\/strong>, <em>19<\/em>, e0304736.<\/p>\n\n\n\n<p class=\"has-text-align-center\">############################################################################<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.joc.4c01533\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"377\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2024BDN-1024x377.jpeg\" alt=\"\" class=\"wp-image-452\" style=\"aspect-ratio:2.7162489894907034;width:496px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2024BDN-1024x377.jpeg 1024w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2024BDN-300x110.jpeg 300w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2024BDN-768x283.jpeg 768w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2024BDN.jpeg 1437w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n<\/div>\n\n\n<p>&#8220;<strong>Regiospecific Synthesis of 1,4-Diaryl-5-Cyano-1,2,3-Triazoles and Their Photoconversion to 2- or 3-Cyanoindoles<\/strong>&#8221; Nusser, B. D.; Jenkins, L. E.; Lin, X.; Zhu, L.  <em>J. Org. Chem<\/em>. <strong>2024<\/strong>, <em>89<\/em>, 12610-12618.<\/p>\n\n\n\n<p class=\"has-text-align-center\">############################################################################<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlehtml\/2023\/ob\/d3ob01003a\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"308\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2023Dan-1024x308.jpg\" alt=\"\" class=\"wp-image-455\" style=\"width:531px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2023Dan-1024x308.jpg 1024w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2023Dan-300x90.jpg 300w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2023Dan-768x231.jpg 768w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2023Dan-1536x463.jpg 1536w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2023Dan-2048x617.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n<\/div>\n\n\n<p>&#8220;<strong>SNAP-Tagging Live Cells via Chelation-Assisted Copper-Catalyzed Azide-Alkyne Cycloaddition<\/strong>&#8221; Stone, D. J.; Macias-Contreras, M.; Crist, S. M.; Bucag, C. F. T.; Seo, G.; Zhu, L. <em>Org. Biomol. Chem.<\/em> <strong>2023<\/strong>, <em>21<\/em>, 7419-7436.<\/p>\n\n\n\n<p class=\"has-text-align-center\">############################################################################<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><a href=\"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/full\/10.1002\/cphc.202300209\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"222\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2023BDN-1024x222.jpg\" alt=\"\" class=\"wp-image-456\" style=\"aspect-ratio:4.613008409129913;width:546px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2023BDN-1024x222.jpg 1024w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2023BDN-300x65.jpg 300w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2023BDN-768x167.jpg 768w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2023BDN.jpg 1299w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n<\/div>\n\n\n<p>&#8220;<strong>Luminescence and Stability of 1,4,5-Triaryl-1,2,3-Triazoles<\/strong>&#8221; Nusser, B. D.; Accardo, J. V.; Zhu, L. <em>ChemPhysChem<\/em> <strong>2023<\/strong>, <em>24<\/em>, e202300209.<\/p>\n\n\n\n<p class=\"has-text-align-center\">############################################################################<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.jpca.2c03668\"><img loading=\"lazy\" decoding=\"async\" width=\"741\" height=\"558\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2022Joe.jpeg\" alt=\"\" class=\"wp-image-458\" style=\"aspect-ratio:1.3280493174812857;width:377px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2022Joe.jpeg 741w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2026\/01\/2022Joe-300x226.jpeg 300w\" sizes=\"auto, (max-width: 741px) 100vw, 741px\" \/><\/a><\/figure>\n<\/div>\n\n\n<p>&#8220;<strong>Excitation Energy-Dependent, Excited-State Intramolecular Proton Transfer-Based Dual Emission in Poor Hydrogen-Bonding Solvents<\/strong>&#8221; Hurley, J. J. M. Hurley; Zhu. L. <em>J. Phys. Chem. A<\/em> <strong>2022<\/strong>, <em>126<\/em>, 5711-5720.<\/p>\n\n\n\n<p class=\"has-text-align-center\">############################################################################<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"136\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/2022-2nd-pub-JMH.gif\" alt=\"\" class=\"wp-image-387\"\/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-text-align-center\"><strong>Triple Emission of 5&#8242;-(para-R-Phenylene)vinylene-2-(2&#8242;-hydroxyphenyl)benzoxazole (PVHBO). Part II: Emission from Anions.<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\">Joseph J. M. Hurley, Quinton J. Meisner, Peijun Guo, Richard D. Schaller, David J. Gosztola, Gary P. Wiederrecht, and Lei Zhu*. J. Phys. Chem. A 2022, 126, <em>7<\/em>, 1062-1075.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><a href=\"https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/acs.jpca.1c10167\"><img loading=\"lazy\" decoding=\"async\" width=\"225\" height=\"225\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link.png\" alt=\"\" class=\"wp-image-382\" style=\"width:63px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link.png 225w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link-150x150.png 150w\" sizes=\"auto, (max-width: 225px) 100vw, 225px\" \/><\/a><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"135\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/PVHBO-paper-1.gif\" alt=\"\" class=\"wp-image-391\" style=\"width:391px;height:auto\"\/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-text-align-center\"><strong>Triple Emission of 5&#8242;-(para-R-Phenylene-2-(2&#8242;-hydroxyphenyl)benzoxazole (PVHBO). Part I: Dual Emission from the Neutral species.<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\">Quinton J. Meisner, Joseph J. M. Hurley, Peijun Guo, Anna R. Blood, Richard D. Schaller, David J. Gosztola, Gary P. Wiederrecht, and Lei Zhu*. J. Phys. Chem. A 2022, 126, <em>7<\/em>, 1033-1061.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jpca.1c10165\"><img loading=\"lazy\" decoding=\"async\" width=\"225\" height=\"225\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link.png\" alt=\"\" class=\"wp-image-382\" style=\"width:63px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link.png 225w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link-150x150.png 150w\" sizes=\"auto, (max-width: 225px) 100vw, 225px\" \/><\/a><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"357\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/2021pub1.gif\" alt=\"\" class=\"wp-image-392\" style=\"width:311px;height:auto\"\/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-text-align-center\"><strong>Hydroxyaromatic Fluorophores<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\">Joseph J. M. Hurley, Quinton J. Meisner, Chen Huang, and Lei Zhu*. ACS Omega 2021, 6, <em>5<\/em>, 3447-3462.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><a href=\"https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/acsomega.0c04611\"><img loading=\"lazy\" decoding=\"async\" width=\"225\" height=\"225\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link.png\" alt=\"\" class=\"wp-image-382\" style=\"width:63px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link.png 225w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link-150x150.png 150w\" sizes=\"auto, (max-width: 225px) 100vw, 225px\" \/><\/a><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"412\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/MMC-2021.jpg\" alt=\"\" class=\"wp-image-393\" style=\"width:354px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/MMC-2021.jpg 800w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/MMC-2021-300x155.jpg 300w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/MMC-2021-768x396.jpg 768w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-text-align-center\"><strong>Power of Genetically Encoded Protein\/Peptide Tags and Bioorthogonal Chemistry in Biological Fluorescence Imaging.<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\">Miguel Macias-Contreras and Lei Zhu*. ChemPhotoChem 2021, 5, <em>3<\/em>, 187-216.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><a href=\"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/cptc.202000215\"><img loading=\"lazy\" decoding=\"async\" width=\"225\" height=\"225\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link.png\" alt=\"\" class=\"wp-image-382\" style=\"width:63px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link.png 225w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link-150x150.png 150w\" sizes=\"auto, (max-width: 225px) 100vw, 225px\" \/><\/a><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n<h1 class=\"wp-block-heading\">Publications 2016-2020<\/h1>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"852\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/Pub-54-1024x852.jpg\" alt=\"\" class=\"wp-image-398\" style=\"width:333px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/Pub-54-1024x852.jpg 1024w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/Pub-54-300x250.jpg 300w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/Pub-54-768x639.jpg 768w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/Pub-54-1536x1278.jpg 1536w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/Pub-54-2048x1703.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-text-align-center\"><strong>The Influence of Amino Substituents on the Signal-output, Selectivity, and Sensitivity of a Hydroxyaromatic 1,2,3-triazolyl Chemosensor for Anions-A Structure-Property Relationship Investigation<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\">Debanjana Ghosh, Shainaz Landge, Lei Zhu, Unodinma Ofulue, Oluwagbotemi A. Akinsoji, Richard D. Govan, Aikohi Ugboya, Vincent Hernandez, Kayley Yates, Arneshia Henderson, Karelle S. Aiken*. J. Phys. Org. Chem., 2020, 33, <em>10<\/em>, e4078.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/poc.4078\"><img loading=\"lazy\" decoding=\"async\" width=\"225\" height=\"225\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link.png\" alt=\"\" class=\"wp-image-382\" style=\"width:63px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link.png 225w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link-150x150.png 150w\" sizes=\"auto, (max-width: 225px) 100vw, 225px\" \/><\/a><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"246\" height=\"246\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/pub-53.webp\" alt=\"\" class=\"wp-image-400\" style=\"width:291px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/pub-53.webp 246w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/pub-53-150x150.webp 150w\" sizes=\"auto, (max-width: 246px) 100vw, 246px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-text-align-center\"><strong>Chapter Twelve &#8211; Expanding the Substrate Selectivity of SNAP\/CLIP-tagging of Intracellular Targets.<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\">Miguel Macias-Contreras, Kevin N. Little, and Lei Zhu*. Methods Enzymol. 2020, 638, 233-257.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0076687920300999\"><img loading=\"lazy\" decoding=\"async\" width=\"225\" height=\"225\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link.png\" alt=\"\" class=\"wp-image-382\" style=\"width:63px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link.png 225w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link-150x150.png 150w\" sizes=\"auto, (max-width: 225px) 100vw, 225px\" \/><\/a><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"306\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/pub-52.gif\" alt=\"\" class=\"wp-image-405\" style=\"width:352px;height:auto\"\/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-text-align-center\"><strong>SNAP\/CLIP-tags and Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC)\/Inverse Electron Demand Diels-Alder (IEDDA) for Intracellular Orthogonal\/Bioorthogonal Labelling.<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\">Miguel Macias-Contreras, Huan He, Kevin N. Little, Justin P. Lee, Ryan P. Campbell, Maksim Royzen, and Lei Zhu*. Bioconjugate Chem. 2020, 31, <em>5<\/em>, 1370-1381.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.bioconjchem.0c00107\"><img loading=\"lazy\" decoding=\"async\" width=\"225\" height=\"225\" src=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link.png\" alt=\"\" class=\"wp-image-382\" style=\"width:63px;height:auto\" srcset=\"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link.png 225w, https:\/\/www.chem.fsu.edu\/~lzhu\/wp-content\/uploads\/2024\/04\/link-150x150.png 150w\" sizes=\"auto, (max-width: 225px) 100vw, 225px\" \/><\/a><\/figure>\n<\/div><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;Copper-Catalyzed Conjugation between Nitrile Imines and Terminal Alkynes&#8221; Weeks, K. N.; Zhu, L. J. Org. Chem. 2025, 90, 8329-8339. ############################################################################ &#8220;DABCO-Catalyzed Nucleophilic Aromatic Substitution and Its Use in Improving the Synthesis of O2-Benzylcytosines as Substrates of CLIP-tag&#8221; Little, K. N.; Ofosu Addai, G.; Stanwood, C. C.; Bucag, C. F. T.; Lin, X.; Chen, B.; Whittington, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-100","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-json\/wp\/v2\/pages\/100","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-json\/wp\/v2\/comments?post=100"}],"version-history":[{"count":27,"href":"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-json\/wp\/v2\/pages\/100\/revisions"}],"predecessor-version":[{"id":460,"href":"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-json\/wp\/v2\/pages\/100\/revisions\/460"}],"wp:attachment":[{"href":"https:\/\/www.chem.fsu.edu\/~lzhu\/wp-json\/wp\/v2\/media?parent=100"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}