“Copper-Catalyzed Conjugation between Nitrile Imines and Terminal Alkynes” Weeks, K. N.; Zhu, L. J. Org. Chem. 2025, 90, 8329-8339.
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“DABCO-Catalyzed Nucleophilic Aromatic Substitution and Its Use in Improving the Synthesis of O2-Benzylcytosines as Substrates of CLIP-tag” Little, K. N.; Ofosu Addai, G.; Stanwood, C. C.; Bucag, C. F. T.; Lin, X.; Chen, B.; Whittington, A. C.; Zhu, L. J. Org. Chem. 2025, 90, 8001-8012.
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“Scalable lipid droplet microarray fabrication, validation, and screening” Bell, T. N., Kusi-Appiah, A. E., Tocci, V., Lyu, P., Zhu, L., Zhu, F., Winkle, D. V., Cao, H., Singh, M. S., Lenhert, S. PLoS ONE 2024, 19, e0304736.
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“Regiospecific Synthesis of 1,4-Diaryl-5-Cyano-1,2,3-Triazoles and Their Photoconversion to 2- or 3-Cyanoindoles” Nusser, B. D.; Jenkins, L. E.; Lin, X.; Zhu, L. J. Org. Chem. 2024, 89, 12610-12618.
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“SNAP-Tagging Live Cells via Chelation-Assisted Copper-Catalyzed Azide-Alkyne Cycloaddition” Stone, D. J.; Macias-Contreras, M.; Crist, S. M.; Bucag, C. F. T.; Seo, G.; Zhu, L. Org. Biomol. Chem. 2023, 21, 7419-7436.
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“Luminescence and Stability of 1,4,5-Triaryl-1,2,3-Triazoles” Nusser, B. D.; Accardo, J. V.; Zhu, L. ChemPhysChem 2023, 24, e202300209.
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“Excitation Energy-Dependent, Excited-State Intramolecular Proton Transfer-Based Dual Emission in Poor Hydrogen-Bonding Solvents” Hurley, J. J. M. Hurley; Zhu. L. J. Phys. Chem. A 2022, 126, 5711-5720.
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Triple Emission of 5′-(para-R-Phenylene)vinylene-2-(2′-hydroxyphenyl)benzoxazole (PVHBO). Part II: Emission from Anions.
Joseph J. M. Hurley, Quinton J. Meisner, Peijun Guo, Richard D. Schaller, David J. Gosztola, Gary P. Wiederrecht, and Lei Zhu*. J. Phys. Chem. A 2022, 126, 7, 1062-1075.
Triple Emission of 5′-(para-R-Phenylene-2-(2′-hydroxyphenyl)benzoxazole (PVHBO). Part I: Dual Emission from the Neutral species.
Quinton J. Meisner, Joseph J. M. Hurley, Peijun Guo, Anna R. Blood, Richard D. Schaller, David J. Gosztola, Gary P. Wiederrecht, and Lei Zhu*. J. Phys. Chem. A 2022, 126, 7, 1033-1061.
Hydroxyaromatic Fluorophores
Joseph J. M. Hurley, Quinton J. Meisner, Chen Huang, and Lei Zhu*. ACS Omega 2021, 6, 5, 3447-3462.
Power of Genetically Encoded Protein/Peptide Tags and Bioorthogonal Chemistry in Biological Fluorescence Imaging.
Miguel Macias-Contreras and Lei Zhu*. ChemPhotoChem 2021, 5, 3, 187-216.
Publications 2016-2020
The Influence of Amino Substituents on the Signal-output, Selectivity, and Sensitivity of a Hydroxyaromatic 1,2,3-triazolyl Chemosensor for Anions-A Structure-Property Relationship Investigation
Debanjana Ghosh, Shainaz Landge, Lei Zhu, Unodinma Ofulue, Oluwagbotemi A. Akinsoji, Richard D. Govan, Aikohi Ugboya, Vincent Hernandez, Kayley Yates, Arneshia Henderson, Karelle S. Aiken*. J. Phys. Org. Chem., 2020, 33, 10, e4078.
Chapter Twelve – Expanding the Substrate Selectivity of SNAP/CLIP-tagging of Intracellular Targets.
Miguel Macias-Contreras, Kevin N. Little, and Lei Zhu*. Methods Enzymol. 2020, 638, 233-257.
SNAP/CLIP-tags and Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC)/Inverse Electron Demand Diels-Alder (IEDDA) for Intracellular Orthogonal/Bioorthogonal Labelling.
Miguel Macias-Contreras, Huan He, Kevin N. Little, Justin P. Lee, Ryan P. Campbell, Maksim Royzen, and Lei Zhu*. Bioconjugate Chem. 2020, 31, 5, 1370-1381.