Dr. Hedi Mattoussi, Distinguished Research Professor

Professional Preparation/Appointments

B.S. Faculty of Sciences Tunis, Tunisia (1982)
Ph.D. Pierre & Marie Curie University (1987)
Postdoc, University of Massachusetts Amherst (1987-1988)
Postdoc, Carnegie Mellon University, (1989-1992)
Habilitation to Direct Research. Pierre & Marie Curie University (1994)
Visiting Scientist, MIT (1995-1997)

Contact Information

Email mattoussi@chem.fsu.edu
Office 4006 CSL 850.645.8615
Lab 4702 CSL 850.645.9408

Programs of Research

Materials, Physical

Research Specialties

Bioanalytical, Chemical Biology, Environment and Energy, Structural Biology, Spectroscopy and Photochemistry

Research Interest

The Mattoussi Lab. focuses on understanding and tailoring the surface properties of colloidal inorganic nanocrystals (e.g., luminescent QDs and metallic nanoclusters, Au nanoparticles and magnetic nanocrystals) and their use in various applications, including in biological imaging and sensing . This entails controlling and optimizing several key aspects of nanoparticle growth, structural and optical characterization, ligand design, and surface coordination. We characterize the surface properties of these nanomaterials using techniques such as photochemistry and NMR spectroscopy. We also develop approaches to control the interactions between these surface-ligated nanomaterials and the surrounding environment as means for energy harvesting.


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Wang, W. Wang, S.E. Donmez, Y. Xin, H. Mattoussi, “Engineering Highly Fluorescent and Colloidally Stable Blue-Emitting CsPbBr3 Nanoplatelets Using Polysalt/PbBr2 Ligands,” Chem. Mater. 2022, 34, 4924−4936. https://doi.org/10.1021/acs.chemmater.2c00082
Du, N. Arabzadeh Nosratabad, Z. Jin, C. Zhang, S. Wang and H. Mattoussi, “N-Heterocyclic Carbene Based Multicoordinating Ligands for Stabilizing Semiconductor Nanocrystals,” J. Am. Chem. Soc. 2021, 143, 1873−1884. DOI: 10.1021/jacs.0c10592
Wang, L. Du, Z. Jin, Y. Xin, and H. Mattoussi, “Enhanced Stabilization and Easy Phase Transfer of CsPbBr3 Perovskite Quantum Dots Promoted by High Affinity Polyzwitterionic Ligands,” J. Am. Chem. Soc. 2020, 142, 12669−12680. https://pubs.acs.org/doi/10.1021/jacs.0c03682
Zhang, Z Jin, B. Zeng, W. Wang, G. Palui, and H. Mattoussi, “Characterizing the Brownian Diffusion of Nanocolloids and Molecular Solutions: Diffusion Ordered NMR Spectroscopy versus Dynamic Light Scattering,” J. Phys. Chem. B 2020, 124, 22, 4631–4650. https://doi.org/10.1021/acs.jpcb.0c02177
Perng, G. Palui, W. Wang and H. Mattoussi, “Elucidating the Role of Surface Coating in the Promotion or Prevention of Protein Corona around Quantum Dots,” Bioconjugate Chem. 2019, 30, 2469−2480. DOI: 10.1021/acs.bioconjchem.9b00549