Dr. Hedi Mattoussi, Distinguished Research Professor

Professional Preparation/Appointments

B.S. Faculty of Sciences Tunis, Tunisia (1982)
Ph.D. Pierre & Marie Curie University (1987)
Postdoc, University of Massachusetts Amherst (1987-1988)
Postdoc, Carnegie Mellon University, (1989-1992)
Habilitation to Direct Research. Pierre & Marie Curie University (1994)
Visiting Scientist, MIT (1995-1997)

Contact Information

Email mattoussi@chem.fsu.edu
Office 4006 CSL 850.645.8615
Lab 4702 CSL 850.645.9408

Programs of Research

Materials, Physical

Research Specialties

Bioanalytical, Chemical Biology, Environment and Energy, Structural Biology, Spectroscopy and Photochemistry

Research Interest

The Mattoussi Lab. focuses on understanding and tailoring the surface properties of colloidal inorganic nanocrystals (e.g., luminescent QDs and metallic nanoclusters, Au nanoparticles and magnetic nanocrystals) and their use in various applications, including in biological imaging and sensing . This entails controlling and optimizing several key aspects of nanoparticle growth, structural and optical characterization, ligand design, and surface coordination. We characterize the surface properties of these nanomaterials using techniques such as photochemistry and NMR spectroscopy. We also develop approaches to control the interactions between these surface-ligated nanomaterials and the surrounding environment as means for energy harvesting.


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Xia, W. Wang, L. Du, F.T. Rabouw, D.J. van den Heuvel, H.C. Gerritsen, H. Mattoussi, and C. de Mello Donega. Förster Resonance Energy Transfer between Colloidal CuInS2/ZnS Quantum Dots and Dark Quenchers. J. Phys. Chem. C 2020,124, 1717-1731.

Jin, A. Kapur, W. Wang, J. Diaz Hernandez, M. Thakur, and H. Mattoussi. The Dual Function of Lipoic Acid Groups as Surface Anchors and Reactive Sites for Implementing Maleimide Coupling Chemistry. J. Chem. Phys. 2019, 151, 64703-1- 64703-9.

Yang, P. Moroz, Z. Jin, D.S. Budkina, N. Sundrani, D. Porotnikov, J. Cassidy, Y. Sugiyama, A.N. Tarnovsky, H. Mattoussi, M. Zamkov. Delayed Photoluminescence in Metal-Conjugated Fluorophores. J. Am. Chem. Soc. 2019, 141, 11286-11297.

Du, W. Wang, C. Zhang, Z. Jin, G. Palui, and H. Mattoussi. A Versatile Coordinating Ligand for Coating Semiconductor, Metal and Metal-Oxide Nanocrystals. Chem. Mater. 2018, 30, 7269–7279.

Zeng G. Palui, C. Zhang, N. Zhan, W. Wang, X. Ji, B. Chen, and H. Mattoussi. Characterization of the Ligand Capping of Hydrophobic CdSe-ZnS Quantum Dots using NMR Spectroscopy. Chem. Mater. 2018, 30, 225−238.