Dr. Roper, Michael 

Mar 28, 2019

Faculty

FLORIDA STATE   /   PEOPLE   /   FACULTY

Dr. Michael Roper, Professor

Dr. Michael Roper
RESEARCH WEBSITE

Professional Preparation/Appointments

B.S. University of Texas at Austin (1998)
Ph.D., University of Florida (2003)
Postdoc, University of Virginia (2003-2006)

Contact Information

Email mroper@fsu.edu
Office 4007 CSL 850.644.1846
Lab 4200 CSL  

Programs of Research

Analytical, Biochemistry

research specialties

Bioanalytical, Chemical Biology

Research Interest

The Roper laboratory develops new analytical methods and techniques to investigate biological signaling. Our main biological interest is how the secretion of multiple peptides and small molecules from islets of Langerhans contribute to proper glucose clearance in the body. The reason why we are interested is that defects in this process are associated with metabolic diseases, such as type 2 diabetes. We develop separation, mass spectrometric, and optical assays to measure these components with high sensitivity and temporal resolution, and utilize microfluidic devices to achieve highly integrated systems.

Faculty Interview

Publications

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Mukhitov, N.; Adablah, J. E.; Roper, M. G. Gene expression patterns in synchronized islet populations. Islets 2019, 11, 21-32.
Adams, A. G.; Bulusu, R. K. M.; Mukhitov, N.; Mendoza-Cortes, J. L.; Roper, M. G. Online measurement of glucose consumption from HepG2 cells using an integrated bioreactor and enzymatic assay. Analytical Chemistry 2019, 91, 5184-5190.
Evans, K.; Wang, X.; Roper, M. G. Chiral micellar electrokinetic chromatographic separation for determination of L- and D- primary amines released from murine islets of Langerhans. Analytical Methods  2019, 11, 1276-1283.
Bandak, B.; Yi, L.; Roper, M. G. Microfluidic-enabled quantitative measurements of insulin release dynamics from single islets of Langerhans in response to 5-palmitic acid hydroxy stearic acid. Lab on a Chip  2018, 18, 2873-2882.
Filla, R. T.; Schrell, A. M.; Coulton, J. B.; Edwards, J. L.; Roper, M. G. Frequency-modulated continuous flow analysis electrospray ionization mass spectrometry (FM-CFA-ESI-MS) for sample multiplexing. Analytical Chemistry  2018, 90, 2414-2419.