FSU-Bruker Virtual Colloquium on

Trapped Ion Mobility Spectrometry /
Mass Spectrometry (TIMS/MS)

Fundamentals and Applications

March 28, 2022 (EDT time zone)

Chair: Anouk Rijs
10:50 – 11:00 am Foreword
11:00 – 11:25 am Vicki Wysocki, The Ohio State University, USA
  Surface-Induced Dissociation in a Bruker timsTOF Pro
11:25 – 11:50 am Fanny Caroline Liu, Florida State University, USA
  Tandem-Trapped Ion Mobility Spectrometry/Mass Spectrometry (tTIMS/MS) for structural analysis of native glycoprotein complexes
11:50 – 12:15 pm Robin Park, Bruker Daltonics, USA
  TIMScore™ and 4D-Proteomics™
12:15 – 12:40 pm Roman Fisher, University of Oxford, United Kingdom
  TimsTOF in clinical proteomics
12:40 – 12:50 pm Intermission (10 min)
Chair: Christian Bleiholder
12:50 – 1:15 pm Edwin de Pauw, Université de Liège, Belgium
  Analysis of persistent pollutants by GC-TIMS: dioxins, furans and PCBs
1:15 – 1:40 pm Florian Meier, Jena University Hospital, Germany
  Exploring post-translational modifications via TIMS and PASEF
1:40 – 2:05 pm Anouk Rijs, Vrije Universiteit Amsterdam, The Netherlands
  Probing peptide and protein aggregation: advances in trapped ion mobility mass spectrometry
2:05 – 2:30 pm John Yates III, The Scripps Research Institute, USA
  Quantitative proteomics with the TIMS TOF Pro – A survey of the cancer conformational landscape with 3D proteomics
2:30 – 2:55 pm Francisco Fernandez-Lima, Florida International University, USA
  Characterization of histone proteoforms using TIMS-(CID, ExD, UVPD) TOF MS/MS strategies



March 29, 2022 (EDT time zone)

Chair: Fanny Caroline Liu
10:50 – 11:00 am Introductory Remarks
11:00 – 11:25 am Matthias Mann, Max-Planck Institute of Biochemistry, Germany
  PASEF timsTOF for single cell proteomics
11:25 – 11:50 am Carlos Afonso, Université de Rouen, France
  Structural analysis of highly complex organic matter by trapped ion mobility coupled with a Fourier transform ion cyclotron resonance mass spectrometer
11:50 – 12:15 pm Cheng Lin, Boston University School of Medicine, USA
  Characterization of isomeric glycans by TIMS-ExD MS/MS
12:15 – 12:40 pm Ying Ge, University of Wisconsin-Madison, USA
  Advancing top-down proteomics through trapped ion mobility spectrometry
12:40 – 12:50 pm Intermission (10 min)
Chair: Florian Meier
12:50 – 1:15 pm Judith Steen, Harvard Medical School and Children’s Hospital, USA
  Leveraging TIMS ToF instruments to study neurodegenerative disease
1:15 – 1:40 pm Johannes Mueller-Reif, OmicEra Diagnostics GmbH, Germany
  Deep and high-throughput urine proteome profiling for the classification of Parkinson’s disease patients
1:40 – 2:05 pm Blaine Roberts, Emory University School of Medicine, USA
  Adding a new dimension: Isomeric lipid profiling for blood-based biomarker development
2:05 – 2:30 pm Christian Bleiholder, Florida State University, USA
  Towards elucidating the glycan shield of viral protein complexes with tandem-trapped ion mobility spectrometry/mass spectrometry
2:30 – 2:40 pm Concluding Remarks